ABSTRACT
OBJECTIVES: Women in menopause have the more mood swings than before menopause. At the same time seem to sexual self-concept and sexual aspects of self-knowledge has a great impact on their mental health. This study aimed to investigate the sexual self-concept and its relationship to depression, stress and anxiety in postmenopausal women's. METHODS: In this descriptive correlation research, 300 of postmenopausal women referred to healthcare and medical treatment centers in Abadeh city were selected by convenience sampling method. The information in this study was collected by using questionnaires of multidimensional sexual self-concept and depression anxiety stress scale 21 (DASS-21). For data analysis, SPSS/17 software was used. RESULTS: The results showed the mean score positive sexual self-concept was 41.03 ± 8.66 and the average score of negative sexual self in women's was 110.32 ± 43.05. As well as scores of depression, stress, and anxiety, 35.67%, 32.33% and 37.67% respectively were in severe level. Positive and negative sexual self-concept scores with scores of stress, anxiety, and depression, of post-menopausal women in the confidence of 0.01, is significantly correlated (P < 0.05). CONCLUSIONS: Being stress, anxiety, and depression in severe level and also a significant correlation between increased stress, anxiety and depression with negative and weak self-concept of women's, it is necessary to devote more careful attention to mental health issues of women's and have appropriate interventions.
Subject(s)
Female , Humans , Anxiety , Delivery of Health Care , Depression , Menopause , Mental Health , Methods , Statistics as Topic , Stress, PsychologicalABSTRACT
Diabetes is one of the most common metabolic disorders and is interrelated to oxidative stress-induced diseases. According to the role of dietary antioxidants in control and prevention of diabetes, this study was aimed to evaluate the effect of green tea extract on serum glucose levels and serum and hepatic total antioxidant capacity [TAC] and lipid [MDA] in diabetic rats. Experimental diabetes in rats was induced by intraperitoneal injection of streptozotocin [55 mg/Kg]. Alcoholic extract of green tea [100, 200 mg/Kg] was given by oral gavage to normal and diabetic rats for 4 weeks. Finally, serum glucose and serum and hepatic levels of MDA and TAC were measured and analyzed statistically. Data showed that green tea extract at dose of 200 mg/Kg significantly decreased the serum glucose levels, serum and hepatic MDA concentration and increased the total antioxidant capacity in diabetic rats [p < 0.05]. Green tea supplementation also increased hepatic TAC in normal rats [p < 0.05]. The antihyperglycemic and antioxidative features of green tea make it an attractive candidate for the prophylactic treatment of diabetes, although further investigation is needed to determine exact dose and duration of supplementation
ABSTRACT
Obesity is a worldwide public health problem that results in comorbidities including diabetes, dyslipidemia, coronary artery disease and some types of cancer. It seems that soy isoflavones can improve obesity and reverse subsequent metabolic disorders. In this study, we assessed the effect of restriction of calorie supplemented with genistein on diet-induced obese rats. Thirty rats obesed with high fat diet were divided randomly into 3 experimental groups [n= I 0] as follows: group I: low calorie diet supplemented with 50mg/kgbw genistein, group2: low calorie diet supplemented with Dimethyl Sulphoxide [DMSO] [as vehicle] and group3: obese control rats with ad libitum access to standard food. After 4 weeks, fasting blood samples were collected and analyzed for biochemical analysis. The results showed that administration of genistein in conjunction with low calorie diet can synergistically improve triglyceride [p=0.005], VLDL [p=0.005], total cholesterol [p=0.002] and LDL-C [P=0.003] and increase HDL-C [p=0.001] but has no effect on body weight and proinflammatory biomarkers [resistin and CRP]. Restriction of calorie also resulted in the decrease of glucose level, TG, TC, LDL, proinflammatory biomarker [CRP] and increase in HDL-C [p<0.05] but has no effect on resistin level. It seems that administration of genistein with restriction of calorie is useful for improvement of hyperlipidemia in obese hyperlipidemic patients
ABSTRACT
To assess the effect of restricting calories with or without daidzein on weight, serum levels of glucose, and inflammatory markers in obese rats. This experimental study was carried out in Jundishapur University, Ahvaz, Iran, from September 2010 to January 2011. Obesity was induced in 30 male Wistar rats [140-160, 6-8 weeks age] after 6 weeks by feeding them a high-fat diet. Then, the rats were divided into 3 groups: obese rats treated with low-calorie diet containing 50 mg/kg daidzein [n=10]; obese rats treated with low-calorie diet containing dimethyl sulfoxide [n=10]; and obese rats that were given ad libitum access to food as the control group [n=10]. After 4 weeks, blood samples were collected in order to analyze the levels of glucose, resistin, and high sensitive C-reactive protein [CRP]. Restriction of calories resulted in decreased blood glucose [p=0.002], and decreased levels of high sensitive CRP [p=0.000], but had no significant effect on resistin level. Daidzein administration had no significant effect on body weight, serum glucose, levels of resistin, and high sensitive CRP. Calorie restriction significantly affected body weight, serum glucose, low-grade inflammation biomarkers, and masked the effect of daidzein
ABSTRACT
To examine the effect of green tea extract on body weight, serum levels of glucose, and lipids in streptozotocin-induced diabetic rats. This experimental study was carried out in the Diabetes Research Center, Ahvaz University of Medical Sciences, Ahvaz, Iran from January 2011 to March 2011. Forty-eight male wistar rats[200-250g] were divided randomly into 6 groups. Diabetes was induced by a single intraperitoneal injection of stereptozotocin [55 mg/kg]. The experimental groups received alcohol extract of green tea leaves [100 mg/kg and 200 mg/kg] for 4 weeks and the body weight of animals were measured every day. Finally, blood samples were collected and analyzed for glucose and lipid profile levels. Administration of green tea extract caused a significant decrease in serum glucose and total cholesterol levels and significantly improved the body weight loss in diabetic rats treated with 200 mg/kg green tea in comparison to diabetic control group. No significant changes were observed in triglyceride [p=0.04], low-density-lipoprotein cholesterol [p=0.000], and high-density-lipoprotein cholesterol levels [p=0.01] following intervention. It appears that green tea extract had both antihyperglycemic and hypocholesterolmic effects in diabetic rats, although further work is needed to determine their mechanism